prod:prod_dcx-login
Cepheid
Team editoriale
Segui
Condividi
2 minuti di lettura
28 aprile 2025
SALUTE RESPIRATORIA
Articolo
Qual è la differenza tra PCR e test antigenico?
Respiratory viral infections remain a significant cause of healthcare visits worldwide, with the COVID-19 pandemic emphasizing the critical need for timely and accurate diagnostic testing. Testing capabilities have advanced in recent years, and various options exist, differing in accuracy, detection window, viral markers, and use cases.
Polymerase Chain Reaction (PCR) and antigen testing are routine techniques for detecting respiratory viruses such as SARS-CoV-2, influenza, and others. Healthcare providers must stay informed about the capabilities and applications of antigen and PCR tests to maximize diagnostic accuracy and ensure efficient resource utilization for better patient care.
View the infographic below to understand how PCT and antigen tests differ.
Riferimenti bibliografici:
1. ADLM Guidance Document on Laboratory Diagnosis of Respiratory Viruses | myadlm.org. Consultato il 27 agosto 2024. https://www.myadlm.org/Science-and-Research/Academy-Guidance/Laboratory-Diagnosis-of-Respiratory-Viruses
2. Hanson KE, Azar MM, Banerjee R, et al. Molecular testing for acute respiratory tract infections: clinical and diagnostic recommendations from the idsa’s diagnostics committee. Clin Infect Dis. 2020;71(10):2744-2751. doi:10:1093/cid/ciaa508
3. Rapid Influenza Diagnostic Tests | Influenza (Flu) | CDC. Consultato il 6 gennaio 2025. https://www.cdc.gov/flu/hcp/testing-methods/clinician_guidance_ridt.html?CDC_AAref_Val=https://www.cdc.gov/flu/professionals/diagnosis/clinician_guidance_ridt.htm
4. Dinnes J, Sharma P, Berhane S, et al. Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection. Cochrane Database Syst Rev. 2022;7(7):CD013705. doi:10:1002/14651858.CD013705.pub3
5. Testing for COVID-19 | COVID-19 | CDC. Consultato il 28 agosto 2024. https://www.cdc.gov/covid/testing/index.html
6. https://www.fda.gov/medical-devices/safety-communications/home-covid-19-antigen-tests-take-steps-reduce-your-risk-false-negative-results-fda-safety. Consultato il 28 agosto 2024. https://www.fda.gov/medical-devices/safety-communications/home-covid-19-antigen-tests-take-steps-reduce-your-risk-false-negative-results-fda-safety
7. Algorithm to assist in the interpretation of influenza testing results and clinical decision-making during periods when influenza viruses are circulating in the community | CDC. Consultato il 27 agosto 2024. https://www.cdc.gov/flu/professionals/diagnosis/algorithm-results-circulating.htm
8. Smith-Jeffcoat SE, Mellis AM, Grijalva CG, et al. SARS-CoV-2 Viral Shedding and Rapid Antigen Test Performance - Respiratory Virus Transmission Network, November 2022-May 2023. MMWR Morb Mortal Wkly Rep. 2024;73(16):365-371. doi:10:15585/mmwr.mm7316a2
9. Uyeki TM, Bernstein HH, Bradley JS, et al. Clinical practice guidelines by the infectious diseases society of america: 2018 update on diagnosis, treatment, chemoprophylaxis, and institutional outbreak management of seasonal influenzaa. Clin Infect Dis. 2019;68(6):e1-e47. doi:10:1093/cid/ciy866
10. Charlton CL, Babady E, Ginocchio CC, et al. Practical guidance for clinical microbiology laboratories: viruses causing acute respiratory tract infections. Clin Microbiol Rev. 2019;32(1). doi:10:1128/CMR.00042-18
11. Davies S, Boller E, Chase J, Beaubrun A, Miller C, Jensen I. A cost-consequence analysis of the Xpert Xpress CoV-2/Flu/RSV plus test strategy for the diagnosis of influenza-like illnesses. J Med Econ. 2024;27(1):430-441. doi:10:1080/13696998:2024:2313391
12. Mojebi A, Wu P, Keeping S, Hale B, Chase JG, Beaubrun A. Clinical impact of rapid molecular diagnostic tests in patients presenting with viral respiratory symptoms: A systematic literature review. PLOS One. 2024;19(6):e0303560. doi:10:1371/journal.pone.0303560
Leggi successivo
MOLTO PIÙ
