prod:prod_dcx-login
Cepheid
Editorial Team
Follow
Share
3m Read
September, 11 2024
ANTIMICROBIAL STEWARDSHIP
Impact Story
PCR Screening at a British Hospital Enables Timely Infection Control
At Royal Liverpool and Broadgreen University Hospitals NHS, the turnaround time for carbapenemase-producing enterobacterales (CPE) testing using culture and phenotypic confirmation was up to 72 hours.
Because there was a lack of rooms to isolate the patients at the hospital, patients could be released before their test results were available.
This delay increased the risk of the spread of CPE, resulting in the loss of beds and ward closures to prevent further spread of CPE. El coste de perder una sola cama era de 200 GBP al día, lo que ascendía a 150.000 GBP si un pabellón con 25 camas se veía obligado a cerrar durante un mes.
Existía una necesidad imperiosa de un método de detección del EPC más rápido para eliminar la posibilidad de que los pacientes contagiaran el EPC o se les diera de alta antes de recibir los resultados de las pruebas.
In order to avoid delays and prevent the spread of CPE, the Royal Liverpool and Broadgreen University Hospitals NHS Trust implemented PCR-based CPE testing using the Xpert® Carba-R test on a GeneXpert® Infinity system to enable faster screening. The Xpert Carba-R test provides results in 50 minutes, significantly reducing the total turnaround time (TAT) from 72 hours to 4 hours.
The expedited TAT allowed room bays to be decanted and decontaminated quickly, reducing the number of beds lost to CPE due to contamination measures by 50%.
“La introducción de las pruebas moleculares rápidas para enterobacterias productoras de carbapenemasas (EPC) nos permitió acortar el tiempo hasta el resultado a cuestión de horas en lugar de días, identificar rápidamente a los pacientes y tomar rápidamente las precauciones necesarias”.
-- Dr. Tim Neal, Mersey Programme Director Microbiology, Department of Microbiology Royal Liverpool University Hospital, Royal Liverpool and Broadgreen University Hospitals NHS Trust
Listen to Dr. Tim Neal, Mersey Programme Director Microbiology, Department of Microbiology Royal Liverpool University Hospital, Royal Liverpool and Broadgreen University Hospitals NHS Trust discuss infection control within his organizations.
Learn more about PCR-based CPE testing using the Xpert® Carba-R test on the GeneXpert® Infinity system to enable effective screening.
CE-IVD. In Vitro Diagnostic Medical Device. Es posible que no esté disponible en todos los países.
*Projections and realized results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions
Referencia:
Corless, C E et al. “Impact of different carbapenemase-producing Enterobacterales screening strategies in a hospital setting.” Infection prevention in practice vol. 2,3 100011. 21 May. 2020 doi:10.1016/j.infpip.2019.100011
Read Next
MÁS INFORMACIÓN
